AIDS, also known as acquired immunodeficiency syndrome (AIDS), is an infection caused by human immunodeficiency virus (HIV) infection, mainly through sexual behavior, blood contact or mother-child contact. After HIV infection, human immune function is suppressed, which is easy to cause virus infection and tumor. Human body infected with HIV will cause the damage of T lymphocytes, cause persistent immunodeficiency
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How does AIDS come into being
Two kinds of glycoproteins, gp120 and gp41, are embedded in the lipoprotein membrane of HIV in vitro. Gp120 and CD4 glycoprotein on the surface of lymphocytes have affinity, and the specific combination of gp41 mediates the fusion of viral membrane and host cell membrane. Therefore, HIV can reach the blood through other methods such as skin and mucous membrane damage and blood, and then choose to invade CD4+ lymphocytes.
After HIV invades CD4+ lymphocytes, under the action of viral reverse transcriptase
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At the initial stage of infection, HIV replicated in large quantities, resulting in viremia and the expression of capsid antigen p24. The clinical manifestation was acute HIV infection. Due to the large number of intracellular replication of HIV, CD4+ lymphocytes were damaged and died, and CD4+T cells decreased significantly. However, under the immune action of the body, CD8+CTL is activated to kill HIV infected cells and produce anti-HIV antibodies. Viremia is quickly cleared and the number of CD4+ lymphocytes is restored.
There are several ways of transmission of AIDS.
AIDS patients' blood, semen, vaginal secretions
bbw dildo , tears, urine, milk, cerebrospinal fluid, AIDS patients and people living with AIDS are contagious, mainly through sexual contact, followed by blood transmission, such as drug users, HIV-infected blood and blood.
1. Sexual transmission: HIV can be transmitted through sexual intercourse. Genital venereal diseases (such as syphilis, gonorrhea, condyloma acuminatum) or ulcers can increase the risk of infection. There are a large number of viruses in the semen or vaginal secretions of people living with HIV, which can spread the virus through anal and vaginal intercourse. The probability of oral sex transmission is relatively small. Unless there is a wound or rupture in the mouth of the healthy person, HIV may be transmitted through blood or semen.
2. Blood transmission:
(1) Blood transfusion transmission: there is HIV in the blood, and people who enter the blood will be infected.
(2) the spread of blood products: some patients (such as hemophiliacs) need to be injected with biological products made from ingredients in the blood.
(3) other: dental surgery, quarrelling, sharing toothbrushes, scrapers, bleeding industries, metal cutting and other aspects, in fact, it is easy to infect AIDS through blood.
3. Transmission of shared needles: the use of unclean needles can spread HIV from one person to another, such as repeated use of needles, drips and so on in hospitals where intravenous drug users share needles.
4. Mother-child transmission: if the mother is infected with AIDS, pregnancy, childbirth and breastfeeding may infect the child. However, if the mother takes anti-AIDS drugs during pregnancy, the baby may be infected with HIV or even completely healthy.
Can kissing spread AIDS?
Does saliva spread AIDS? Generally speaking, kissing does not spread AIDS. HIV exists in infected people's blood, semen, vaginal secretions, tears, urine, milk, cerebrospinal fluid, the content of saliva is very small, will not infect the human virus. Under normal circumstances (there is no massive bleeding in the mouth), only saliva contains HIV virus, in order to achieve the effect of HIV infection, it is necessary to put 2 gallons of saliva into the other person's body. In addition, so far, the scientific community has not found any cases of kissing infection.
It should be noted, however, that the level of HIV in saliva refers to people who do not have oral health problems, and kissing can increase the risk of AIDS if gum disease causes gum bleeding or oral ulcers.